Antibacterial and Antibiofilm Activities from Extracts of Selected Cholistani Plants
Keywords:Antibacterial activity, Cholistani plants, E.coli, K.pneumonia
The Cholistani plants are used as a vital source of medicines by local nomads for a long time. According to recent studies, many pharmacological studies like antibacterial, antiviral, antifungal, and antidiabetic were done, but very few chemistry-based approaches are available. The current study was designed to evaluate the antibacterial potentials of extracts of Cholistani plants. Aqueous, ethanol, and n-hexane extracts were prepared, and extraction was done based on polarity. All the extracts were evaluated for antibacterial activities through the disc diffusion method. The Minimum Inhibitory Concentration (MIC) of each positive extract was measured. The results indicated that the aqueous extract of these plants was more effective than others. The overall trend of antibacterial activity was as follows aqueous >n-hexane >ethanol extracts in terms of solvent. In terms of bacteria, almost all extracts were effective against Klebsiella pneumonia. The overall antibacterial trend was Klebsiella pneumonia>Proteus vulgaris>Staphylococcus aureus>Escherichia coli>Pseudomonas aeuriginosa. The results indicate that Cholistani plants are a rich source of antibacterial agent(s) and can be used in crude or purified form.
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